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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
12.12
Human Site:
T111
Identified Species:
19.05
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
T111
P
A
L
K
D
S
P
T
Q
E
R
E
E
L
F
Chimpanzee
Pan troglodytes
XP_518483
668
77639
T177
P
A
L
K
D
S
P
T
Q
E
R
E
E
L
F
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
S111
C
V
L
F
D
F
V
S
D
P
L
S
D
L
K
Dog
Lupus familis
XP_538927
602
69962
T111
P
A
L
K
D
S
P
T
Q
E
R
E
E
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
I87
I
T
H
N
R
N
V
I
T
E
P
I
Y
P
E
Rat
Rattus norvegicus
XP_001062510
563
65413
L110
K
E
V
K
R
A
G
L
N
E
M
V
E
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
S17
A
K
G
A
P
K
P
S
S
G
G
K
D
G
G
Chicken
Gallus gallus
XP_419321
459
53699
K22
Q
Q
Q
T
P
S
N
K
R
P
S
N
S
A
P
Frog
Xenopus laevis
NP_001087638
506
58853
Y69
K
R
Q
S
S
S
R
Y
N
V
S
N
N
R
E
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
C112
F
V
Q
K
L
R
Q
C
C
V
L
F
D
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
A192
I
P
L
N
E
K
T
A
A
S
E
R
E
E
L
Honey Bee
Apis mellifera
XP_392477
724
84384
D111
R
Q
C
C
V
L
F
D
F
E
S
D
P
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
D109
V
V
F
D
F
I
S
D
P
L
S
D
L
K
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
L73
S
G
F
K
D
G
N
L
K
S
S
G
N
N
N
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
P285
P
N
F
N
E
V
S
P
E
E
R
I
P
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
20
100
N.A.
6.6
20
N.A.
6.6
6.6
6.6
6.6
N.A.
13.3
13.3
N.A.
0
P-Site Similarity:
100
100
33.3
100
N.A.
13.3
33.3
N.A.
26.6
13.3
6.6
13.3
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
0
7
0
7
0
7
7
0
0
0
0
7
0
% A
% Cys:
7
0
7
7
0
0
0
7
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
34
0
0
14
7
0
0
14
20
0
0
% D
% Glu:
0
7
0
0
14
0
0
0
7
47
7
20
34
7
14
% E
% Phe:
7
0
20
7
7
7
7
0
7
0
0
7
0
7
27
% F
% Gly:
0
7
7
0
0
7
7
0
0
7
7
7
0
7
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
0
0
0
0
7
0
7
0
0
0
14
0
0
7
% I
% Lys:
14
7
0
40
0
14
0
7
7
0
0
7
0
7
7
% K
% Leu:
0
0
34
0
7
7
0
14
0
7
14
0
7
40
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
7
0
20
0
7
14
0
14
0
0
14
14
7
7
% N
% Pro:
27
7
0
0
14
0
27
7
7
14
7
0
14
7
7
% P
% Gln:
7
14
20
0
0
0
7
0
20
0
0
0
0
0
0
% Q
% Arg:
7
7
0
0
14
7
7
0
7
0
27
7
0
7
0
% R
% Ser:
7
0
0
7
7
34
14
14
7
14
34
7
7
0
7
% S
% Thr:
0
7
0
7
0
0
7
20
7
0
0
0
0
0
0
% T
% Val:
7
20
7
0
7
7
14
0
0
14
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _